6VZB

Crystal structure of cytochrome P450 NasF5053 S284A-V288A mutant variant from Streptomyces sp. NRRL F-5053 in the cyclo-L-Trp-L-Pro-bound state

6VZB の概要

• エントリーDOI: 10.2210/pdb6vzb/pdb
• 分子名称: cytochrome P450 NasF5053, (3S,8aS)-3-(1H-indol-3-ylmethyl)hexahydropyrrolo[1,2-a]pyrazine-1,4-dione, SODIUM ION, ... (5 entities in total)
• 機能のキーワード: biosynthetic protein, cytochrome p450, cyclodipeptide, regio-selecitivty, stereo-selectivity, pyrroloindoline alkaloids, radical mediated reaction, f5053, streptomyces, oxidoreductase
• 由来する生物種: Streptomyces sp. NRRL F-5053
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 44621.15

構造登録者

Luo, Z.,Jia, X.,Sun, C.,Qu, X.,Kobe, B. (登録日: 2020-02-28, 公開日: 2020-11-11, 最終更新日: 2023-10-11)

• 主引用文献: Sun, C.,Luo, Z.,Zhang, W.,Tian, W.,Peng, H.,Lin, Z.,Deng, Z.,Kobe, B.,Jia, X.,Qu, X.; Molecular basis of regio- and stereo-specificity in biosynthesis of bacterial heterodimeric diketopiperazines.; Nat Commun, 11:6251-6251, 2020; PubMed: 33288748; DOI: 10.1038/s41467-020-20022-5

実験手法

X-RAY DIFFRACTION (1.68 Å)