6VYV

Human mAbs broadly protect against infection of arthritiogenic alphaviruses by recognizing conserved elements of the MXR8 receptor binding domain

6VYV の概要

• エントリーDOI: 10.2210/pdb6vyv/pdb
• EMDBエントリー: 21473
• 分子名称: E1 glycoprotein, E2 glycoprotein, Fab CHK-265 heavy chain, ... (4 entities in total)
• 機能のキーワード: virus, monoclonal antibody, complex, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Ross river virus (strain T48) (RRV); 詳細
• タンパク質・核酸の鎖数: 16
• 化学式量合計: 510368.87

構造登録者

Miller, A.S.,Kuhn, R.J. (登録日: 2020-02-27, 公開日: 2020-08-26, 最終更新日: 2024-03-06)

• 主引用文献: Powell, L.A.,Miller, A.,Fox, J.M.,Kose, N.,Klose, T.,Kim, A.S.,Bombardi, R.,Tennekoon, R.N.,Dharshan de Silva, A.,Carnahan, R.H.,Diamond, M.S.,Rossmann, M.G.,Kuhn, R.J.,Crowe Jr., J.E.; Human mAbs Broadly Protect against Arthritogenic Alphaviruses by Recognizing Conserved Elements of the Mxra8 Receptor-Binding Site.; Cell Host Microbe, 28:699-711.e7, 2020; PubMed: 32783883; DOI: 10.1016/j.chom.2020.07.008

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