6VXV

Crystal structure of cyclo-L-Trp-L-Pro-bound cytochrome P450 NasF5053 from Streptomyces sp. NRRL F-5053

Summary for 6VXV

Entry DOI	10.2210/pdb6vxv/pdb
Descriptor	cytochrome P450 NasF5053, SODIUM ION, (3S,8aS)-3-(1H-indol-3-ylmethyl)hexahydropyrrolo[1,2-a]pyrazine-1,4-dione, ... (6 entities in total)
Functional Keywords	biosynthetic protein, cytochrome p450, cyclodipeptide, regio-selecitivty, stereo-selectivity, pyrroloindoline alkaloids, radical mediated reaction, f5053, streptomyces, oxidoreductase
Biological source	Streptomyces sp. NRRL F-5053
Total number of polymer chains	1
Total formula weight	44705.28
Authors	Luo, Z.,Jia, X.,Sun, C.,Qu, X.,Kobe, B. (deposition date: 2020-02-24, release date: 2020-11-11, Last modification date: 2023-10-11)
Primary citation	Sun, C.,Luo, Z.,Zhang, W.,Tian, W.,Peng, H.,Lin, Z.,Deng, Z.,Kobe, B.,Jia, X.,Qu, X. Molecular basis of regio- and stereo-specificity in biosynthesis of bacterial heterodimeric diketopiperazines. Nat Commun, 11:6251-6251, 2020 Cited by PubMed: 33288748 DOI: 10.1038/s41467-020-20022-5 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation