6VO8
X-ray structure of the Cj1427 in the presence of NADH and GDP-D-glycero-D-mannoheptose, an essential NAD-dependent dehydrogenase from Campylobacter jejuni
Summary for 6VO8
Entry DOI | 10.2210/pdb6vo8/pdb |
Related | 6vo6 |
Descriptor | Putative sugar-nucleotide epimerase/dehydratease, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, [[(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-6-oxidanylidene-3~{H}-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{S},5~{S},6~{S})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-3,4,5-tris(oxidanyl)oxan-2-yl] hydrogen phosphate, ... (4 entities in total) |
Functional Keywords | capsular polysaccharide, oxidoreductase, dehydrogenase, isomerase |
Biological source | Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168) |
Total number of polymer chains | 2 |
Total formula weight | 76040.18 |
Authors | Spencer, K.D.,Anderson, T.K.,Thoden, J.B.,Huddleston, J.P.,Raushel, F.M.,Holden, H.M. (deposition date: 2020-01-30, release date: 2020-03-25, Last modification date: 2023-10-11) |
Primary citation | Huddleston, J.P.,Anderson, T.K.,Spencer, K.D.,Thoden, J.B.,Raushel, F.M.,Holden, H.M. Structural Analysis of Cj1427, an Essential NAD-Dependent Dehydrogenase for the Biosynthesis of the Heptose Residues in the Capsular Polysaccharides ofCampylobacter jejuni. Biochemistry, 59:1314-1327, 2020 Cited by PubMed: 32168450DOI: 10.1021/acs.biochem.0c00096 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
Download full validation report