6VO2
Crystal structure of Staphylococcus aureus ketol-acid reductoisomerase in complex with Mg, NADPH and inhibitor.
Summary for 6VO2
| Entry DOI | 10.2210/pdb6vo2/pdb |
| Descriptor | Ketol-acid reductoisomerase (NADP(+)), MAGNESIUM ION, 3-(methylsulfonyl)-2-oxopropanoic acid, ... (5 entities in total) |
| Functional Keywords | reductoisomerase, inhibitor, complex, metal binding protein |
| Biological source | Staphylococcus aureus |
| Total number of polymer chains | 2 |
| Total formula weight | 76035.91 |
| Authors | Bayaraa, T.,Patel, K.M.,Guddat, L.W. (deposition date: 2020-01-29, release date: 2020-04-08, Last modification date: 2023-10-11) |
| Primary citation | Bayaraa, T.,Kurz, J.L.,Patel, K.M.,Hussein, W.M.,Bilyj, J.K.,West, N.P.,Schenk, G.,McGeary, R.P.,Guddat, L.W. Discovery, Synthesis and Evaluation of a Ketol-Acid Reductoisomerase Inhibitor. Chemistry, 26:8958-8968, 2020 Cited by PubMed: 32198779DOI: 10.1002/chem.202000899 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.59 Å) |
Structure validation
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