6VFL

BG505-SOSIP model reconstructed by subparticle extraction and refinement from a tetrahedral nanoparticle T33_dn10

6VFL の概要

• エントリーDOI: 10.2210/pdb6vfl/pdb
• EMDBエントリー: 21185 21186
• 分子名称: BG505-SOSIPv5.2(7S) - gp120, BG505-SOSIPv5.2(7S) - gp41, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: nanoparticle, rosetta, de novo protein design, hiv env, de novo protein
• 由来する生物種: synthetic construct; 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 243677.32

構造登録者

Antanasijevic, A.,Ward, A.B. (登録日: 2020-01-05, 公開日: 2020-07-22, 最終更新日: 2020-08-26)

• 主引用文献: Antanasijevic, A.,Ueda, G.,Brouwer, P.J.M.,Copps, J.,Huang, D.,Allen, J.D.,Cottrell, C.A.,Yasmeen, A.,Sewall, L.M.,Bontjer, I.,Ketas, T.J.,Turner, H.L.,Berndsen, Z.T.,Montefiori, D.C.,Klasse, P.J.,Crispin, M.,Nemazee, D.,Moore, J.P.,Sanders, R.W.,King, N.P.,Baker, D.,Ward, A.B.; Structural and functional evaluation of de novo-designed, two-component nanoparticle carriers for HIV Env trimer immunogens.; Plos Pathog., 16:e1008665-e1008665, 2020; PubMed: 32780770; DOI: 10.1371/journal.ppat.1008665

実験手法

ELECTRON MICROSCOPY (4.14 Å)