6VAW

Peanut lectin complexed with N-beta-D-galactopyranosyl-L-succinamoyl derivative (NGS)

Summary for 6VAW

• Entry DOI: 10.2210/pdb6vaw/pdb
• Descriptor: Galactose-binding lectin, N-[(2R,3R,4S,5R,6S)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]-N'-[(1-{[(2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-methoxytetrahydro-2H-pyran-2-yl]methyl}-1H-1,2,3-triazol-4-yl)methyl]butanediamide, MANGANESE (II) ION, ... (5 entities in total)
• Functional Keywords: beta-galactosylamides, beta-thiogalactosides, peanut agglutinin, glycomimetics, sugar binding protein
• Biological source: Arachis hypogaea (Peanut)
• Total number of polymer chains: 4
• Total formula weight: 103357.89

Authors

Otero, L.H.,Primo, E.D.,Cagnoni, A.J.,Klinke, S.,Goldbaum, F.A.,Uhrig, M.L. (deposition date: 2019-12-18, release date: 2020-10-28, Last modification date: 2023-10-11)

• Primary citation: Cagnoni, A.J.,Primo, E.D.,Klinke, S.,Cano, M.E.,Giordano, W.,Marino, K.V.,Kovensky, J.,Goldbaum, F.A.,Uhrig, M.L.,Otero, L.H.; Crystal structures of peanut lectin in the presence of synthetic beta-N- and beta-S-galactosides disclose evidence for the recognition of different glycomimetic ligands.; Acta Crystallogr D Struct Biol, 76:1080-1091, 2020; PubMed: 33135679; DOI: 10.1107/S2059798320012371

Experimental method

X-RAY DIFFRACTION (1.75 Å)