6V9V

Structure of TRPA1 modified by Bodipy-iodoacetamide with bound calcium, LMNG

Summary for 6V9V

Entry DOI	10.2210/pdb6v9v/pdb
EMDB information	21127 21128 21129 21130 21131 21537 21538
Descriptor	Transient receptor potential cation channel subfamily A member 1, ~{N}-[[2,2-bis(fluoranyl)-10,12-dimethyl-1,3-diaza-2$l^{4}-boratricyclo[7.3.0.0^{3,7}]dodeca-4,6,9,11-tetraen-4-yl]methyl]ethanamide, CALCIUM ION (3 entities in total)
Functional Keywords	transient receptor potential subfamily a member 1, membrane protein, transport protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	4
Total formula weight	511914.92
Authors	Zhao, J.,Lin King, J.V.,Paulsen, C.E.,Cheng, Y.,Julius, D. (deposition date: 2019-12-16, release date: 2020-05-06, Last modification date: 2020-09-16)
Primary citation	Zhao, J.,Lin King, J.V.,Paulsen, C.E.,Cheng, Y.,Julius, D. Irritant-evoked activation and calcium modulation of the TRPA1 receptor. Nature, 585:141-145, 2020 Cited by PubMed: 32641835 DOI: 10.1038/s41586-020-2480-9 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.6 Å)

Structure validation