6V7O

Structural Elucidation of Peptide Binding to KLHL-12, a Substrate Specific Adapter Protein in a Cul3-Ring E3 Ligase Complex

Summary for 6V7O

Entry DOI	10.2210/pdb6v7o/pdb
Descriptor	Kelch-like protein 12, Dvl3-peptide (2 entities in total)
Functional Keywords	e3 ligase, klhl-12, ubiquitination, ligase
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	67713.87
Authors	Zhao, B. (deposition date: 2019-12-09, release date: 2020-02-19, Last modification date: 2023-10-11)
Primary citation	Zhao, B.,Payne, W.G.,Sai, J.,Lu, Z.,Olejniczak, E.T.,Fesik, S.W. Structural Elucidation of Peptide Binding to KLHL-12, a Substrate Specific Adapter Protein in a Cul3-Ring E3 Ligase Complex. Biochemistry, 59:964-969, 2020 Cited by PubMed: 32032490 DOI: 10.1021/acs.biochem.9b01073 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation