6V74

Crystal Structure of Human PKM2 in Complex with L-asparagine

Summary for 6V74

Entry DOI	10.2210/pdb6v74/pdb
Descriptor	Pyruvate kinase PKM, POTASSIUM ION, GLYCEROL, ... (10 entities in total)
Functional Keywords	glycolytic enzyme, tetramer, amino acid binding, transferase
Biological source	Homo sapiens (Human)
Total number of polymer chains	4
Total formula weight	244057.32
Authors	Nandi, S.,Dey, M. (deposition date: 2019-12-07, release date: 2020-03-18, Last modification date: 2023-10-11)
Primary citation	Nandi, S.,Dey, M. Biochemical and structural insights into how amino acids regulate pyruvate kinase muscle isoform 2. J.Biol.Chem., 295:5390-5403, 2020 Cited by PubMed: 32144209 DOI: 10.1074/jbc.RA120.013030 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.32 Å)

Structure validation