6V6A

Inhibitory scaffolding of the ancient MAPK, ERK7

Summary for 6V6A

Entry DOI	10.2210/pdb6v6a/pdb
Descriptor	Mitogen-activated protein kinase, Apical Cap Protein 9 (AC9), 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywords	protein kinase, mapk, intrinsically-disordered protein, scaffold, signaling protein
Biological source	Toxoplasma gondii More
Total number of polymer chains	4
Total formula weight	88895.20
Authors	Dewangan, P.S.,O'Shaughnessy, W.J.,Back, P.S.,Hu, X.,Bradley, P.J.,Reese, M.L. (deposition date: 2019-12-04, release date: 2020-05-27, Last modification date: 2023-10-11)
Primary citation	Back, P.S.,O'Shaughnessy, W.J.,Moon, A.S.,Dewangan, P.S.,Hu, X.,Sha, J.,Wohlschlegel, J.A.,Bradley, P.J.,Reese, M.L. Ancient MAPK ERK7 is regulated by an unusual inhibitory scaffold required forToxoplasmaapical complex biogenesis. Proc.Natl.Acad.Sci.USA, 117:12164-12173, 2020 Cited by PubMed: 32409604 DOI: 10.1073/pnas.1921245117 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation