6V6A

Inhibitory scaffolding of the ancient MAPK, ERK7

6V6A の概要

• エントリーDOI: 10.2210/pdb6v6a/pdb
• 分子名称: Mitogen-activated protein kinase, Apical Cap Protein 9 (AC9), 1,2-ETHANEDIOL, ... (4 entities in total)
• 機能のキーワード: protein kinase, mapk, intrinsically-disordered protein, scaffold, signaling protein
• 由来する生物種: Toxoplasma gondii; 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 88895.20

構造登録者

Dewangan, P.S.,O'Shaughnessy, W.J.,Back, P.S.,Hu, X.,Bradley, P.J.,Reese, M.L. (登録日: 2019-12-04, 公開日: 2020-05-27, 最終更新日: 2023-10-11)

• 主引用文献: Back, P.S.,O'Shaughnessy, W.J.,Moon, A.S.,Dewangan, P.S.,Hu, X.,Sha, J.,Wohlschlegel, J.A.,Bradley, P.J.,Reese, M.L.; Ancient MAPK ERK7 is regulated by an unusual inhibitory scaffold required forToxoplasmaapical complex biogenesis.; Proc.Natl.Acad.Sci.USA, 117:12164-12173, 2020; PubMed: 32409604; DOI: 10.1073/pnas.1921245117

実験手法

X-RAY DIFFRACTION (2.1 Å)