6V3M

Crystal structure of 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (IspF) Burkholderia pseudomallei in compomplex with ligand HGN-0961 (BSI110840)

Summary for 6V3M

• Entry DOI: 10.2210/pdb6v3m/pdb
• Descriptor: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, ZINC ION, 5-{[(propan-2-yl)carbamoyl]amino}-1,3,4-thiadiazole-2-sulfonamide, ... (7 entities in total)
• Functional Keywords: ssgcid, structural genomics, seattle structural genomics center for infectious disease, burkholderia pseudomallei, 2-c-methyl-d-erythritol 2, 4-cyclodiphosphate synthase, hgn-0961, lyase
• Biological source: Burkholderia pseudomallei (strain 1710b)
• Total number of polymer chains: 3
• Total formula weight: 60164.45

Authors

Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2019-11-26, release date: 2020-12-09, Last modification date: 2023-10-11)

• Primary citation: Abendroth, J.,Yano, J.K.,Pierce, P.G.,Horn, J.R.,Hagen, T.J.,Horanyi, P.S.,Lorimer, D.D.,Edwards, T.E.; Crystal structure of 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (IspF) Burkholderia pseudomallei in compomplex with ligand HGN-0961 (BSI110840); to be published,

Experimental method

X-RAY DIFFRACTION (1.55 Å)