6V18

immune receptor complex

Summary for 6V18

Entry DOI	10.2210/pdb6v18/pdb
Related	6V0Y 6V13 6V15
Descriptor	HLA class II histocompatibility antigen, DR alpha chain, HLA class II histocompatibility antigen, DRB1-4 beta chain, Fibrinogen beta, ... (8 entities in total)
Functional Keywords	immune receptor, complex, immune system
Biological source	Homo sapiens (Human) More
Total number of polymer chains	5
Total formula weight	98418.23
Authors	Lim, J.J.,Rossjohn, J. (deposition date: 2019-11-20, release date: 2020-11-25, Last modification date: 2023-11-15)
Primary citation	Lim, J.J.,Jones, C.M.,Loh, T.J.,Ting, Y.T.,Zareie, P.,Loh, K.L.,Felix, N.J.,Suri, A.,McKinnon, M.,Stevenaert, F.,Sharma, R.K.,Klareskog, L.,Malmstrom, V.,Baker, D.G.,Purcell, A.W.,Reid, H.H.,La Gruta, N.L.,Rossjohn, J. The shared susceptibility epitope of HLA-DR4 binds citrullinated self-antigens and the TCR. Sci Immunol, 6:-, 2021 Cited by PubMed: 33863750 DOI: 10.1126/sciimmunol.abe0896 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.35 Å)

Structure validation