6UVS

Human Connexin-26 (Low pH open conformation)

Summary for 6UVS

• Entry DOI: 10.2210/pdb6uvs/pdb
• Related: 6UVR 6UVT
• EMDB information: 20914 20915 20916
• Descriptor: Gap junction beta-2 protein (1 entity in total)
• Functional Keywords: gap junction channel, membrane protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 12
• Total formula weight: 314579.34

Authors

Khan, A.K.,Jagielnicki, M.,Purdy, M.D.,Yeager, M. (deposition date: 2019-11-04, release date: 2020-04-29, Last modification date: 2024-03-06)

• Primary citation: Khan, A.K.,Jagielnicki, M.,McIntire, W.E.,Purdy, M.D.,Dharmarajan, V.,Griffin, P.R.,Yeager, M.; A Steric "Ball-and-Chain" Mechanism for pH-Mediated Regulation of Gap Junction Channels.; Cell Rep, 31:107482-107482, 2020; PubMed: 32320665; DOI: 10.1016/j.celrep.2020.03.046

Experimental method

ELECTRON MICROSCOPY (4.2 Å)