6UUD

Crystal structure of antibody 5D5 in complex with PfCSP N-terminal peptide

Summary for 6UUD

• Entry DOI: 10.2210/pdb6uud/pdb
• Descriptor: 5D5 Antibody Fab, heavy chain, 5D5 Antibody Fab, light chain, Circumsporozoite protein, ... (6 entities in total)
• Functional Keywords: malaria, antibody, immune system
• Biological source: Mus musculus (mouse); More
• Total number of polymer chains: 3
• Total formula weight: 49927.73

Authors

Thai, E.,Scally, S.W.,Julien, J.P. (deposition date: 2019-10-30, release date: 2020-07-15, Last modification date: 2024-04-03)

• Primary citation: Thai, E.,Costa, G.,Weyrich, A.,Murugan, R.,Oyen, D.,Flores-Garcia, Y.,Prieto, K.,Bosch, A.,Valleriani, A.,Wu, N.C.,Pholcharee, T.,Scally, S.W.,Wilson, I.A.,Wardemann, H.,Julien, J.P.,Levashina, E.A.; A high-affinity antibody against the CSP N-terminal domain lacks Plasmodium falciparum inhibitory activity.; J.Exp.Med., 217:-, 2020; PubMed: 32790871; DOI: 10.1084/jem.20200061

Experimental method

X-RAY DIFFRACTION (1.85 Å)