6UOE

3-25 Fab germline-reversion variant bound to an HCMV gB-derived peptide

Summary for 6UOE

Entry DOI	10.2210/pdb6uoe/pdb
Descriptor	3-25 Fab heavy chain, 3-25 Fab light chain, Envelope glycoprotein B, ... (6 entities in total)
Functional Keywords	fragment antigen-binding, viral peptide, hcmv gb, immune system-viral protein complex, immune system/viral protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	3
Total formula weight	49908.46
Authors	Wrapp, D.,McLellan, J.S. (deposition date: 2019-10-14, release date: 2020-07-29, Last modification date: 2023-10-11)
Primary citation	Ye, X.,Su, H.,Wrapp, D.,Freed, D.C.,Li, F.,Yuan, Z.,Tang, A.,Li, L.,Ku, Z.,Xiong, W.,Jaijyan, D.,Zhu, H.,Wang, D.,McLellan, J.S.,Zhang, N.,Fu, T.M.,An, Z. Recognition of a highly conserved glycoprotein B epitope by a bivalent antibody neutralizing HCMV at a post-attachment step. Plos Pathog., 16:e1008736-e1008736, 2020 Cited by PubMed: 32745149 DOI: 10.1371/journal.ppat.1008736 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation