6UOE

3-25 Fab germline-reversion variant bound to an HCMV gB-derived peptide

6UOE の概要

• エントリーDOI: 10.2210/pdb6uoe/pdb
• 分子名称: 3-25 Fab heavy chain, 3-25 Fab light chain, Envelope glycoprotein B, ... (6 entities in total)
• 機能のキーワード: fragment antigen-binding, viral peptide, hcmv gb, immune system-viral protein complex, immune system/viral protein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 49908.46

構造登録者

Wrapp, D.,McLellan, J.S. (登録日: 2019-10-14, 公開日: 2020-07-29, 最終更新日: 2023-10-11)

• 主引用文献: Ye, X.,Su, H.,Wrapp, D.,Freed, D.C.,Li, F.,Yuan, Z.,Tang, A.,Li, L.,Ku, Z.,Xiong, W.,Jaijyan, D.,Zhu, H.,Wang, D.,McLellan, J.S.,Zhang, N.,Fu, T.M.,An, Z.; Recognition of a highly conserved glycoprotein B epitope by a bivalent antibody neutralizing HCMV at a post-attachment step.; Plos Pathog., 16:e1008736-e1008736, 2020; PubMed: 32745149; DOI: 10.1371/journal.ppat.1008736

実験手法

X-RAY DIFFRACTION (1.8 Å)