6UF2

NMR structure of biofilm-related Se0862 from Synechococcus elongatus

6UF2 の概要

• エントリーDOI: 10.2210/pdb6uf2/pdb
• NMR情報: BMRB: 30676
• 分子名称: Biofilm-related protein (1 entity in total)
• 機能のキーワード: secretion, biofilm, unknown function
• 由来する生物種: Synechococcus elongatus (strain PCC 7942)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 14425.34

構造登録者

Zhang, N.,LiWang, A.L. (登録日: 2019-09-23, 公開日: 2020-09-30, 最終更新日: 2024-05-15)

主引用文献

Zhang, N.,Chang, Y.G.,Tseng, R.,Ovchinnikov, S.,Schwarz, R.,LiWang, A.
Solution NMR structure of Se0862, a highly conserved cyanobacterial protein involved in biofilm formation.
Protein Sci., 29:2274-2280, 2020

PubMed Abstract: Biofilms are accumulations of microorganisms embedded in extracellular matrices that protect against external factors and stressful environments. Cyanobacterial biofilms are ubiquitous and have potential for treatment of wastewater and sustainable production of biofuels. But the underlying mechanisms regulating cyanobacterial biofilm formation are unclear. Here, we report the solution NMR structure of a protein, Se0862, conserved across diverse cyanobacterial species and involved in regulation of biofilm formation in the cyanobacterium Synechococcus elongatus PCC 7942. Se0862 is a class α+β protein with ααββββαα topology and roll architecture, consisting of a four-stranded β-sheet that is flanked by four α-helices on one side. Conserved surface residues constitute a hydrophobic pocket and charged regions that are likely also present in Se0862 orthologs.

PubMed: 32949024
DOI: 10.1002/pro.3952

実験手法

SOLUTION NMR