6UB9

Crystal structure of tryptophan synthase from M. tuberculosis - AMINOACRYLATE- AND BRD6309-BOUND FORM

Replaces:  6DUA

Summary for 6UB9

• Entry DOI: 10.2210/pdb6ub9/pdb
• Descriptor: Tryptophan synthase alpha chain, 1,2-ETHANEDIOL, Tryptophan synthase beta chain, ... (11 entities in total)
• Functional Keywords: plp, heterotetramer, amino acid biosynthesis, substrate channeling, allostery, structural genomics, center for structural genomics of infectious diseases, csgid, lyase-lyase inhibitor complex, lyase/lyase inhibitor
• Biological source: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv); More
• Total number of polymer chains: 8
• Total formula weight: 292439.78

Authors

Chang, C.,Michalska, K.,Maltseva, N.I.,Jedrzejczak, R.,McCarren, P.,Nag, P.P.,Joachimiak, A.,Satchell, K.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2019-09-11, release date: 2019-09-25, Last modification date: 2023-10-11)

• Primary citation: Chang, C.,Michalska, K.,Maltseva, N.I.,Jedrzejczak, R.,McCarren, P.,Nag, P.P.,Joachimiak, A.,Satchell, K.,Center for Structural Genomics of Infectious Diseases (CSGID); Crystal structure of tryptophan synthase from M. tuberculosis - AMINOACRYLATE- AND BRD6309-BOUND FORM; To be Published,

Experimental method

X-RAY DIFFRACTION (2.783 Å)