6U6O
Crystal structure of a vaccine-elicited anti-HIV-1 rhesus macaque antibody DH846
Summary for 6U6O
Entry DOI | 10.2210/pdb6u6o/pdb |
Descriptor | DH846 Fab heavy chain, DH846 Fab light chain (3 entities in total) |
Functional Keywords | fab fragment, hiv, antibody, immune system, rhesus macaque, vaccine-elicited |
Biological source | Macaca mulatta (Rhesus monkey) More |
Total number of polymer chains | 2 |
Total formula weight | 47412.69 |
Authors | Chen, W.-H.,Choe, M.,Saunders, K.O.,Joyce, M.G. (deposition date: 2019-08-30, release date: 2021-03-24, Last modification date: 2023-10-11) |
Primary citation | Cai, F.,Chen, W.H.,Wu, W.,Jones, J.A.,Choe, M.,Gohain, N.,Shen, X.,LaBranche, C.,Eaton, A.,Sutherland, L.,Lee, E.M.,Hernandez, G.E.,Wu, N.R.,Scearce, R.,Seaman, M.S.,Moody, M.A.,Santra, S.,Wiehe, K.,Tomaras, G.D.,Wagh, K.,Korber, B.,Bonsignori, M.,Montefiori, D.C.,Haynes, B.F.,de Val, N.,Joyce, M.G.,Saunders, K.O. Structural and genetic convergence of HIV-1 neutralizing antibodies in vaccinated non-human primates. Plos Pathog., 17:e1009624-e1009624, 2021 Cited by PubMed: 34086838DOI: 10.1371/journal.ppat.1009624 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.806 Å) |
Structure validation
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