6U6O

Crystal structure of a vaccine-elicited anti-HIV-1 rhesus macaque antibody DH846

Summary for 6U6O

• Entry DOI: 10.2210/pdb6u6o/pdb
• Descriptor: DH846 Fab heavy chain, DH846 Fab light chain (3 entities in total)
• Functional Keywords: fab fragment, hiv, antibody, immune system, rhesus macaque, vaccine-elicited
• Biological source: Macaca mulatta (Rhesus monkey); More
• Total number of polymer chains: 2
• Total formula weight: 47412.69

Authors

Chen, W.-H.,Choe, M.,Saunders, K.O.,Joyce, M.G. (deposition date: 2019-08-30, release date: 2021-03-24, Last modification date: 2023-10-11)

• Primary citation: Cai, F.,Chen, W.H.,Wu, W.,Jones, J.A.,Choe, M.,Gohain, N.,Shen, X.,LaBranche, C.,Eaton, A.,Sutherland, L.,Lee, E.M.,Hernandez, G.E.,Wu, N.R.,Scearce, R.,Seaman, M.S.,Moody, M.A.,Santra, S.,Wiehe, K.,Tomaras, G.D.,Wagh, K.,Korber, B.,Bonsignori, M.,Montefiori, D.C.,Haynes, B.F.,de Val, N.,Joyce, M.G.,Saunders, K.O.; Structural and genetic convergence of HIV-1 neutralizing antibodies in vaccinated non-human primates.; Plos Pathog., 17:e1009624-e1009624, 2021; PubMed: 34086838; DOI: 10.1371/journal.ppat.1009624

Experimental method

X-RAY DIFFRACTION (2.806 Å)