6U5S
NTD of GluA2 in complex with CNIH3 - with antagonist ZK200775 - in pseudo-symmetric global conformation
Summary for 6U5S
Entry DOI | 10.2210/pdb6u5s/pdb |
EMDB information | 20654 |
Descriptor | Glutamate receptor 2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total) |
Functional Keywords | ionotropic glutamate receptor, ampa receptor, cornichon, auxiliary subunit, ion channel, ligand gated ion channel, synaptic transmission, excitatory synaptic transmission, neurotransmitter receptor, stargazin, tarp, zk200775, lipid, mpqx, transport protein |
Biological source | Rattus norvegicus (Rat) |
Total number of polymer chains | 4 |
Total formula weight | 402165.34 |
Authors | Nakagawa, T. (deposition date: 2019-08-28, release date: 2019-12-04, Last modification date: 2020-07-29) |
Primary citation | Nakagawa, T. Structures of the AMPA receptor in complex with its auxiliary subunit cornichon. Science, 366:1259-1263, 2019 Cited by PubMed: 31806817DOI: 10.1126/science.aay2783 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.07 Å) |
Structure validation
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