6U33
Structure-based discovery of a novel small-molecule inhibitor of methicillin-resistant S. aureus
Summary for 6U33
Entry DOI | 10.2210/pdb6u33/pdb |
Related | 6U2S |
Descriptor | Bi-component leukocidin LukED subunit D, NICKEL (II) ION (3 entities in total) |
Functional Keywords | alpha-toxin, pvl, leukocidins, mrsa, toxin |
Biological source | Staphylococcus aureus |
Total number of polymer chains | 1 |
Total formula weight | 34259.22 |
Authors | Liu, J.,Kozhaya, L.,Torres, V.J.,Unutmaz, D.,Lu, M. (deposition date: 2019-08-21, release date: 2020-03-25, Last modification date: 2023-10-11) |
Primary citation | Liu, J.,Kozhaya, L.,Torres, V.J.,Unutmaz, D.,Lu, M. Structure-based discovery of a small-molecule inhibitor of methicillin-resistantStaphylococcus aureusvirulence. J.Biol.Chem., 295:5944-5959, 2020 Cited by PubMed: 32179646DOI: 10.1074/jbc.RA120.012697 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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