6U31

The crystal structure of 4-(1H-imidazol-1-yl)benzoate-bound CYP199A4

6U31 の概要

• エントリーDOI: 10.2210/pdb6u31/pdb
• 分子名称: Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE, 4-(1H-imidazol-1-yl)benzoic acid, ... (5 entities in total)
• 機能のキーワード: cytochrome p450, 4-(1h-imidazol-1-yl)benzoic acid, oxidoreductase
• 由来する生物種: Rhodopseudomonas palustris (strain HaA2)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 45427.55

構造登録者

Podgorski, M.N.,Bruning, J.B.,Bell, S.G. (登録日: 2019-08-21, 公開日: 2020-08-26, 最終更新日: 2023-10-11)

• 主引用文献: Podgorski, M.N.,Coleman, T.,Giang, P.D.,Wang, C.R.,Bruning, J.B.,Bernhardt, P.V.,De Voss, J.J.,Bell, S.G.; To Be, or Not to Be, an Inhibitor: A Comparison of Azole Interactions with and Oxidation by a Cytochrome P450 Enzyme.; Inorg.Chem., 61:236-245, 2022; PubMed: 34910500; DOI: 10.1021/acs.inorgchem.1c02786

実験手法

X-RAY DIFFRACTION (1.578 Å)