6TWV

Crystal structure of the haemagglutinin mutant (Gln226Leu) from an H10N7 seal influenza virus isolated in Germany with human receptor analogue, 6'SLN

6TWV の概要

• エントリーDOI: 10.2210/pdb6twv/pdb
• 関連するBIRD辞書のPRD_ID: PRD_900046
• 分子名称: Hemagglutinin HA1, Hemagglutinin HA2, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• 機能のキーワード: receptor binding, fusion of virus membrane with host plasma membrane, viral protein
• 由来する生物種: Influenza A virus (A/harbour seal/Germany/1/2014(H10N7)); 詳細
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 340247.05

構造登録者

Zhang, J.,Xiong, X.,Purkiss, A.,Walker, P.,Gamblin, S.,Skehel, J.J. (登録日: 2020-01-13, 公開日: 2020-10-21, 最終更新日: 2024-01-24)

• 主引用文献: Herfst, S.,Zhang, J.,Richard, M.,McBride, R.,Lexmond, P.,Bestebroer, T.M.,Spronken, M.I.J.,de Meulder, D.,van den Brand, J.M.,Rosu, M.E.,Martin, S.R.,Gamblin, S.J.,Xiong, X.,Peng, W.,Bodewes, R.,van der Vries, E.,Osterhaus, A.D.M.E.,Paulson, J.C.,Skehel, J.J.,Fouchier, R.A.M.; Hemagglutinin Traits Determine Transmission of Avian A/H10N7 Influenza Virus between Mammals.; Cell Host Microbe, 28:602-613.e7, 2020; PubMed: 33031770; DOI: 10.1016/j.chom.2020.08.011

実験手法

X-RAY DIFFRACTION (2.55 Å)