6TVW

Structure of native gp41 derived peptide fusion inhibitor

This is a non-PDB format compatible entry.

Summary for 6TVW

• Entry DOI: 10.2210/pdb6tvw/pdb
• Descriptor: Envelope glycoprotein, Transmembrane protein gp41,Envelope glycoprotein gp160 (3 entities in total)
• Functional Keywords: inhibitor, helix bundle, hiv, viral protein
• Biological source: Human immunodeficiency virus 1; More
• Total number of polymer chains: 2
• Total formula weight: 8458.48

Authors

Huhmann, S.,Nyakatura, E.K.,Rohrhofer, A.,Schmidt, B.,Eichler, J.,Moschner, J.,Roth, C.,Koksch, B. (deposition date: 2020-01-10, release date: 2021-01-27, Last modification date: 2024-07-10)

• Primary citation: Huhmann, S.,Nyakatura, E.K.,Rohrhofer, A.,Moschner, J.,Schmidt, B.,Eichler, J.,Roth, C.,Koksch, B.; Systematic Evaluation of Fluorination as Modification for Peptide-Based Fusion Inhibitors against HIV-1 Infection.; Chembiochem, 22:3443-3451, 2021; PubMed: 34605595; DOI: 10.1002/cbic.202100417

Experimental method

X-RAY DIFFRACTION (1.45 Å)