6TTM
Hyoscyamine 6-hydroxylase in complex with N-oxalylglycine and hyoscyamine
Summary for 6TTM
| Entry DOI | 10.2210/pdb6ttm/pdb |
| Related | 6TTN 6TTO |
| Descriptor | Hyoscyamine 6 beta-hydroxylase, DI(HYDROXYETHYL)ETHER, [(1S,5R)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] (2S)-3-hydroxy-2-phenylpropanoate, ... (9 entities in total) |
| Functional Keywords | jelly-roll, non-heme, 2-oxoglutarate, oxidoreductase |
| Biological source | Datura metel (Hindu datura) |
| Total number of polymer chains | 1 |
| Total formula weight | 40676.49 |
| Authors | Kluza, A.,Kurpiewska, K.,Mrugala, B.,Porebski, P.J.,Niedzialkowska, E.,Minor, W.,Borowski, T. (deposition date: 2019-12-29, release date: 2020-03-18, Last modification date: 2024-01-24) |
| Primary citation | Kluza, A.,Wojdyla, Z.,Mrugala, B.,Kurpiewska, K.,Porebski, P.J.,Niedzialkowska, E.,Minor, W.,Weiss, M.S.,Borowski, T. Regioselectivity of hyoscyamine 6 beta-hydroxylase-catalysed hydroxylation as revealed by high-resolution structural information and QM/MM calculations. Dalton Trans, 49:4454-4469, 2020 Cited by PubMed: 32182320DOI: 10.1039/d0dt00302f PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.91 Å) |
Structure validation
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