6TTM

Hyoscyamine 6-hydroxylase in complex with N-oxalylglycine and hyoscyamine

6TTM の概要

• エントリーDOI: 10.2210/pdb6ttm/pdb
• 関連するPDBエントリー: 6TTN 6TTO
• 分子名称: Hyoscyamine 6 beta-hydroxylase, DI(HYDROXYETHYL)ETHER, [(1S,5R)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] (2S)-3-hydroxy-2-phenylpropanoate, ... (9 entities in total)
• 機能のキーワード: jelly-roll, non-heme, 2-oxoglutarate, oxidoreductase
• 由来する生物種: Datura metel (Hindu datura)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 40676.49

構造登録者

Kluza, A.,Kurpiewska, K.,Mrugala, B.,Porebski, P.J.,Niedzialkowska, E.,Minor, W.,Borowski, T. (登録日: 2019-12-29, 公開日: 2020-03-18, 最終更新日: 2024-01-24)

• 主引用文献: Kluza, A.,Wojdyla, Z.,Mrugala, B.,Kurpiewska, K.,Porebski, P.J.,Niedzialkowska, E.,Minor, W.,Weiss, M.S.,Borowski, T.; Regioselectivity of hyoscyamine 6 beta-hydroxylase-catalysed hydroxylation as revealed by high-resolution structural information and QM/MM calculations.; Dalton Trans, 49:4454-4469, 2020; PubMed: 32182320; DOI: 10.1039/d0dt00302f

実験手法

X-RAY DIFFRACTION (1.91 Å)