6TTA

Haddock model of NDM-1/quercetin complex

6TTA の概要

• エントリーDOI: 10.2210/pdb6tta/pdb
• NMR情報: BMRB: 26952
• 分子名称: Metallo beta lactamase NDM-1, ZINC ION, 3,5,7,3',4'-PENTAHYDROXYFLAVONE (3 entities in total)
• 機能のキーワード: complex, inhibitor, quercetin, new-delhi metallo-beta-lactamase-1, haddock, antimicrobial resistance, metal binding protein
• 由来する生物種: Klebsiella pneumoniae
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 24408.01

構造登録者

Riviere, G.,Oueslati, S.,Gayral, M.,Crechet, J.B.,Nhiri, N.,Jacquet, E.,Cintrat, J.C.,Giraud, F.,van Heijenoort, C.,Lescop, E.,Pethe, S.,Iorga, B.I.,Naas, T.,Guittet, E.,Morellet, N. (登録日: 2019-12-26, 公開日: 2021-01-13, 最終更新日: 2024-05-15)

• 主引用文献: Riviere, G.,Oueslati, S.,Gayral, M.,Crechet, J.B.,Nhiri, N.,Jacquet, E.,Cintrat, J.C.,Giraud, F.,van Heijenoort, C.,Lescop, E.,Pethe, S.,Iorga, B.I.,Naas, T.,Guittet, E.,Morellet, N.; NMR Characterization of the Influence of Zinc(II) Ions on the Structural and Dynamic Behavior of the New Delhi Metallo-beta-Lactamase-1 and on the Binding with Flavonols as Inhibitors.; Acs Omega, 5:10466-10480, 2020; PubMed: 32426604; DOI: 10.1021/acsomega.0c00590

実験手法

SOLUTION NMR