Summary for 6TT5
Entry DOI | 10.2210/pdb6tt5/pdb |
Descriptor | Protein artemis, 1,2-ETHANEDIOL, ZINC ION, ... (5 entities in total) |
Functional Keywords | endonuclease, dna repair, v(d)j recombination, nhej recombination, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 42334.99 |
Authors | Yosaatmadja, Y.,Goubin, S.,Newman, J.A.,Mukhopadhyay, S.M.M.,Dannerfjord, A.A.,Burgess-Brown, N.A.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.,Bountra, C.,Gileadi, O. (deposition date: 2019-12-23, release date: 2020-02-12, Last modification date: 2024-01-24) |
Primary citation | Yosaatmadja, Y.,Baddock, H.T.,Newman, J.A.,Bielinski, M.,Gavard, A.E.,Mukhopadhyay, S.M.M.,Dannerfjord, A.A.,Schofield, C.J.,McHugh, P.J.,Gileadi, O. Structural and mechanistic insights into the Artemis endonuclease and strategies for its inhibition. Nucleic Acids Res., 49:9310-9326, 2021 Cited by PubMed: 34387696DOI: 10.1093/nar/gkab693 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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