6TSH

Beta-galactosidase in complex with deoxygalacto-nojirimycin

Summary for 6TSH

Entry DOI	10.2210/pdb6tsh/pdb
EMDB information	10563
Descriptor	Beta-galactosidase, MAGNESIUM ION, (2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol, ... (4 entities in total)
Functional Keywords	bgal, nojirimycin, sugar binding protein
Biological source	Escherichia coli
Total number of polymer chains	4
Total formula weight	474331.25
Authors	Saur, M.,Hartshorn, M.J.,Dong, J.,Reeks, J.,Bunkoczi, G.,Jhoti, H.,Williams, P.A. (deposition date: 2019-12-20, release date: 2020-01-08, Last modification date: 2024-05-22)
Primary citation	Saur, M.,Hartshorn, M.J.,Dong, J.,Reeks, J.,Bunkoczi, G.,Jhoti, H.,Williams, P.A. Fragment-based drug discovery using cryo-EM. Drug Discov Today, 25:485-490, 2020 Cited by PubMed: 31877353 DOI: 10.1016/j.drudis.2019.12.006 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.3 Å)

Structure validation