6TN3
Crystal Structure of Aspergillus fumigatus UDP-N-acetylglucosamine pyrophosphorylase in complex with GlcNAc-1P
Summary for 6TN3
Entry DOI | 10.2210/pdb6tn3/pdb |
Descriptor | UDP-N-acetylglucosamine pyrophosphorylase, PHOSPHATE ION, 2-acetamido-2-deoxy-1-O-phosphono-alpha-D-glucopyranose, ... (4 entities in total) |
Functional Keywords | aspergillus fumigatus, anti-fungal, pyrophosphorylase, transferase |
Biological source | Aspergillus fumigatus Af293 |
Total number of polymer chains | 2 |
Total formula weight | 113983.34 |
Authors | Raimi, O.G.,Guerrero, R.H. (deposition date: 2019-12-05, release date: 2020-04-01, Last modification date: 2024-01-24) |
Primary citation | Raimi, O.G.,Hurtado-Guerrero, R.,Borodkin, V.,Ferenbach, A.,Urbaniak, M.D.,Ferguson, M.A.J.,van Aalten, D.M.F. A mechanism-inspired UDP- N -acetylglucosamine pyrophosphorylase inhibitor. Rsc Chem Biol, 1:13-25, 2020 Cited by PubMed: 34458745DOI: 10.1039/c9cb00017h PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.282 Å) |
Structure validation
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