6TJA

Crystal structure of the SVS_A2 protein (W79F,G83L mutant) from ancestral sequence reconstruction at 2.27 A resolution

6TJA の概要

• エントリーDOI: 10.2210/pdb6tja/pdb
• 分子名称: SVS_variant_AS1, DI(HYDROXYETHYL)ETHER (3 entities in total)
• 機能のキーワード: terpene cyclase, engineered enzyme, biosynthetic protein
• 由来する生物種: Streptomyces sp. CWA1
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 81304.06

構造登録者

Rudraraju, R.,Schnell, R.,Schneider, G. (登録日: 2019-11-25, 公開日: 2020-12-09, 最終更新日: 2024-01-24)

• 主引用文献: Schriever, K.,Saenz-Mendez, P.,Rudraraju, R.S.,Hendrikse, N.M.,Hudson, E.P.,Biundo, A.,Schnell, R.,Syren, P.O.; Engineering of Ancestors as a Tool to Elucidate Structure, Mechanism, and Specificity of Extant Terpene Cyclase.; J.Am.Chem.Soc., 143:3794-3807, 2021; PubMed: 33496585; DOI: 10.1021/jacs.0c10214

実験手法

X-RAY DIFFRACTION (2.27 Å)