6TGG
scFv-1SM3 in complex with glycopeptide containing an sp2-imino sugar
Summary for 6TGG
Entry DOI | 10.2210/pdb6tgg/pdb |
Descriptor | ScFv_SM3, Mucin-1, 1,2-ETHANEDIOL, ... (5 entities in total) |
Functional Keywords | antibody, scfv, antigen tn, iminosugar, anti cancer vaccine, conformational analysis, antitumor protein |
Biological source | Mus musculus (House mouse) More |
Total number of polymer chains | 2 |
Total formula weight | 26893.54 |
Authors | Bermejo, I.A.,Navo, C.D.,Castro-Lopez, J.,Samchez-Fernandez, E.M.,Guerreiro, A.,Avenoza, A.,Busto, J.H.,Garcia-Martin, F.,Nishimura, S.I.,Garcia-Fernandez, J.M.,Ortiz-Mellet, C.,Bernardes, G.J.L.,Hurtado-Guerrero, R.,Peregrina, J.M.,Corzana, F. (deposition date: 2019-11-15, release date: 2020-04-08, Last modification date: 2024-01-24) |
Primary citation | Bermejo, I.A.,Navo, C.D.,Castro-Lopez, J.,Guerreiro, A.,Jimenez-Moreno, E.,Sanchez Fernandez, E.M.,Garcia-Martin, F.,Hinou, H.,Nishimura, S.I.,Garcia Fernandez, J.M.,Mellet, C.O.,Avenoza, A.,Busto, J.H.,Bernardes, G.J.L.,Hurtado-Guerrero, R.,Peregrina, J.M.,Corzana, F. Synthesis, conformational analysis and in vivo assays of an anti-cancer vaccine that features an unnatural antigen based on an sp 2 -iminosugar fragment. Chem Sci, 11:3996-4006, 2020 Cited by PubMed: 34122869DOI: 10.1039/c9sc06334j PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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