6TGG

scFv-1SM3 in complex with glycopeptide containing an sp2-imino sugar

6TGG の概要

• エントリーDOI: 10.2210/pdb6tgg/pdb
• 分子名称: ScFv_SM3, Mucin-1, 1,2-ETHANEDIOL, ... (5 entities in total)
• 機能のキーワード: antibody, scfv, antigen tn, iminosugar, anti cancer vaccine, conformational analysis, antitumor protein
• 由来する生物種: Mus musculus (House mouse); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 26893.54

構造登録者

Bermejo, I.A.,Navo, C.D.,Castro-Lopez, J.,Samchez-Fernandez, E.M.,Guerreiro, A.,Avenoza, A.,Busto, J.H.,Garcia-Martin, F.,Nishimura, S.I.,Garcia-Fernandez, J.M.,Ortiz-Mellet, C.,Bernardes, G.J.L.,Hurtado-Guerrero, R.,Peregrina, J.M.,Corzana, F. (登録日: 2019-11-15, 公開日: 2020-04-08, 最終更新日: 2024-01-24)

• 主引用文献: Bermejo, I.A.,Navo, C.D.,Castro-Lopez, J.,Guerreiro, A.,Jimenez-Moreno, E.,Sanchez Fernandez, E.M.,Garcia-Martin, F.,Hinou, H.,Nishimura, S.I.,Garcia Fernandez, J.M.,Mellet, C.O.,Avenoza, A.,Busto, J.H.,Bernardes, G.J.L.,Hurtado-Guerrero, R.,Peregrina, J.M.,Corzana, F.; Synthesis, conformational analysis and in vivo assays of an anti-cancer vaccine that features an unnatural antigen based on an sp 2 -iminosugar fragment.; Chem Sci, 11:3996-4006, 2020; PubMed: 34122869; DOI: 10.1039/c9sc06334j

実験手法

X-RAY DIFFRACTION (2 Å)