6TEC

Crystal Structure of full-length Human Lysyl Hydroxylase LH3 - Cocrystal with Fe2+, Mn2+, UDP-Xylose

6TEC の概要

• エントリーDOI: 10.2210/pdb6tec/pdb
• 分子名称: Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, URIDINE-5'-DIPHOSPHATE-XYLOPYRANOSE, ... (9 entities in total)
• 機能のキーワード: collagen, lysyl hydroxylase, hydroxylysine, galactosyltransferase, glucosyltransferase, transferase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 84527.29

構造登録者

Chiapparino, A.,De Giorgi, F.,Scietti, L.,Faravelli, S.,Roscioli, T.,Forneris, F. (登録日: 2019-11-11, 公開日: 2021-05-19, 最終更新日: 2024-02-07)

• 主引用文献: Mattoteia, D.,Chiapparino, A.,Fumagalli, M.,De Marco, M.,De Giorgi, F.,Negro, L.,Pinnola, A.,Faravelli, S.,Roscioli, T.,Scietti, L.,Forneris, F.; Identification of Regulatory Molecular 'Hot Spots' for LH/PLOD Collagen Glycosyltransferase Activity; Int J Mol Sci, 2023; DOI: 10.3390/ijms241311213

実験手法

X-RAY DIFFRACTION (2.4 Å)