6TDG
Crystal structure of Aspergillus fumigatus Glucosamine-6-phosphate N-acetyltransferase 1 in complex with compound 2
Summary for 6TDG
Entry DOI | 10.2210/pdb6tdg/pdb |
Descriptor | Glucosamine 6-phosphate N-acetyltransferase, ACETYL COENZYME *A, 2-chloranyl-3-(4~{H}-1,2,4-triazol-3-yl)aniline, ... (4 entities in total) |
Functional Keywords | fragment screening, anti fungal, aspergillus fumigatus, inhibitor, transferase |
Biological source | Aspergillus fumigatus Af293 |
Total number of polymer chains | 1 |
Total formula weight | 22130.31 |
Authors | Raimi, O.G.,Stanley, M.,Lockhart, D. (deposition date: 2019-11-08, release date: 2020-04-29, Last modification date: 2024-01-24) |
Primary citation | Lockhart, D.E.A.,Stanley, M.,Raimi, O.G.,Robinson, D.A.,Boldovjakova, D.,Squair, D.R.,Ferenbach, A.T.,Fang, W.,van Aalten, D.M.F. Targeting a critical step in fungal hexosamine biosynthesis. J.Biol.Chem., 295:8678-8691, 2020 Cited by PubMed: 32341126DOI: 10.1074/jbc.RA120.012985 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.74 Å) |
Structure validation
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