6TDF

Crystal structure of Aspergillus fumigatus Glucosamine-6-phosphate N-acetyltransferase 1 in complex with compound 3

6TDF の概要

• エントリーDOI: 10.2210/pdb6tdf/pdb
• 分子名称: Glucosamine 6-phosphate N-acetyltransferase, ACETYL COENZYME *A, 2-[[3,5-bis(chloranyl)-4-(4~{H}-1,2,4-triazol-3-yl)phenyl]-(2-hydroxyethyl)amino]ethanol, ... (5 entities in total)
• 機能のキーワード: fragment screening, anti fungal, aspergillus fumigatus, inhibitor, transferase
• 由来する生物種: Aspergillus fumigatus Af293
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 22512.99

構造登録者

Raimi, O.G.,Stanley, M.,Lockhart, D. (登録日: 2019-11-08, 公開日: 2020-04-29, 最終更新日: 2024-01-24)

• 主引用文献: Lockhart, D.E.A.,Stanley, M.,Raimi, O.G.,Robinson, D.A.,Boldovjakova, D.,Squair, D.R.,Ferenbach, A.T.,Fang, W.,van Aalten, D.M.F.; Targeting a critical step in fungal hexosamine biosynthesis.; J.Biol.Chem., 295:8678-8691, 2020; PubMed: 32341126; DOI: 10.1074/jbc.RA120.012985

実験手法

X-RAY DIFFRACTION (2.01 Å)