6TD0

Crystal structure of vaborbactam bound to KPC-2

Summary for 6TD0

Entry DOI	10.2210/pdb6td0/pdb
Descriptor	Carbapenem-hydrolyzing beta-lactamase KPC, Vaborbactam, GLYCEROL, ... (5 entities in total)
Functional Keywords	inhibitor, boronate, beta-lactamase, antimicrobial protein
Biological source	Klebsiella pneumoniae
Total number of polymer chains	1
Total formula weight	31768.27
Authors	Tooke, C.L.,Hinchliffe, P.,Spencer, J. (deposition date: 2019-11-07, release date: 2020-01-22, Last modification date: 2024-01-24)
Primary citation	Tooke, C.L.,Hinchliffe, P.,Krajnc, A.,Mulholland, A.J.,Brem, J.,Schofield, C.J.,Spencer, J. Cyclic boronates as versatile scaffolds for KPC-2 beta-lactamase inhibition. Rsc Med Chem, 11:491-496, 2020 Cited by PubMed: 33479650 DOI: 10.1039/c9md00557a PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (0.99 Å)

Structure validation