6T9S

Human Butyrylcholinesterase in complex with 2-(N-hydroxyimino)-N-[(1S)-3-{4-[(2-methyl-1H-imidazol-1-yl)methyl]-1H-1,2,3-triazol-1-yl}-1- phenylpropyl]acetamide

6T9S の概要

• エントリーDOI: 10.2210/pdb6t9s/pdb
• 分子名称: Cholinesterase, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(5-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• 機能のキーワード: butyrylcholinesterase, complex, oxime, hydrolase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 62334.00

構造登録者

Brazzolotto, X.,Sinko, G.,Marakovic, N.,Knezevic, A. (登録日: 2019-10-28, 公開日: 2020-07-15, 最終更新日: 2024-01-31)

• 主引用文献: Marakovic, N.,Knezevic, A.,Roncevic, I.,Brazzolotto, X.,Kovarik, Z.,Sinko, G.; Enantioseparation, in vitro testing, and structural characterization of triple-binding reactivators of organophosphate-inhibited cholinesterases.; Biochem.J., 477:2771-2790, 2020; PubMed: 32639532; DOI: 10.1042/BCJ20200192

実験手法

X-RAY DIFFRACTION (2.7 Å)