6T93
Nucleosome with OCT4-SOX2 motif at SHL-6
Summary for 6T93
Entry DOI | 10.2210/pdb6t93/pdb |
EMDB information | 10408 |
Descriptor | Histone H3.1, Histone H4, Histone H2A type 1-B/E, ... (6 entities in total) |
Functional Keywords | nucleosome, oct4, sox2, transcription factor, transcription |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 10 |
Total formula weight | 206572.25 |
Authors | Michael, A.K.,Kempf, G.,Cavadini, S.,Bunker, R.D.,Thoma, N.H. (deposition date: 2019-10-25, release date: 2020-05-06, Last modification date: 2024-05-22) |
Primary citation | Michael, A.K.,Grand, R.S.,Isbel, L.,Cavadini, S.,Kozicka, Z.,Kempf, G.,Bunker, R.D.,Schenk, A.D.,Graff-Meyer, A.,Pathare, G.R.,Weiss, J.,Matsumoto, S.,Burger, L.,Schubeler, D.,Thoma, N.H. Mechanisms of OCT4-SOX2 motif readout on nucleosomes. Science, 368:1460-1465, 2020 Cited by PubMed: 32327602DOI: 10.1126/science.abb0074 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.49 Å) |
Structure validation
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