6T93

Nucleosome with OCT4-SOX2 motif at SHL-6

Summary for 6T93

• Entry DOI: 10.2210/pdb6t93/pdb
• EMDB information: 10408
• Descriptor: Histone H3.1, Histone H4, Histone H2A type 1-B/E, ... (6 entities in total)
• Functional Keywords: nucleosome, oct4, sox2, transcription factor, transcription
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 10
• Total formula weight: 206572.25

Authors

Michael, A.K.,Kempf, G.,Cavadini, S.,Bunker, R.D.,Thoma, N.H. (deposition date: 2019-10-25, release date: 2020-05-06, Last modification date: 2020-07-08)

• Primary citation: Michael, A.K.,Grand, R.S.,Isbel, L.,Cavadini, S.,Kozicka, Z.,Kempf, G.,Bunker, R.D.,Schenk, A.D.,Graff-Meyer, A.,Pathare, G.R.,Weiss, J.,Matsumoto, S.,Burger, L.,Schubeler, D.,Thoma, N.H.; Mechanisms of OCT4-SOX2 motif readout on nucleosomes.; Science, 368:1460-1465, 2020; PubMed: 32327602; DOI: 10.1126/science.abb0074

Experimental method

ELECTRON MICROSCOPY (3.49 Å)