6T7K

Crystal Structure of Prolyl-tRNA synthetase (ProRS, Proline--tRNA ligase) from Plasmodium falciparum in complex with NCP-26 and L-Proline

6T7K の概要

• エントリーDOI: 10.2210/pdb6t7k/pdb
• 分子名称: Proline--tRNA ligase, PROLINE, ~{N}-(2,3-dihydro-1~{H}-inden-2-yl)-3-(piperidin-1-ylcarbonylamino)pyrazine-2-carboxamide, ... (5 entities in total)
• 機能のキーワード: trna, proline, aminoacyl-trna synthetase, ligase, protein biosynthesis, atp binding
• 由来する生物種: Plasmodium falciparum (isolate 3D7)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 60310.91

構造登録者

Johansson, C.,Wang, J.,Tye, M.,Payne, N.C.,Mazitschek, R.,Thompson, A.,Arrowsmith, C.H.,Bountra, C.,Edwards, A.,Oppermann, U.C.T. (登録日: 2019-10-22, 公開日: 2020-11-18, 最終更新日: 2024-01-24)

• 主引用文献: Johansson, C.,Wang, J.,Tye, M.,Payne, N.C.,Mazitschek, R.,Thompson, A.,Arrowsmith, C.H.,Bountra, C.,Edwards, A.,Oppermann, U.C.T.; Crystal Structure of Prolyl-tRNA synthetase (ProRS, Proline--tRNA ligase) from Plasmodium falciparum in complex with NCP-26 and L-Proline; To Be Published,

実験手法

X-RAY DIFFRACTION (1.79 Å)