6T2B

Glycoside hydrolase family 109 from Akkermansia muciniphila in complex with GalNAc and NAD+.

6T2B の概要

• エントリーDOI: 10.2210/pdb6t2b/pdb
• 分子名称: Glycosyl hydrolase family 109 protein 2, 2-acetamido-2-deoxy-alpha-D-galactopyranose, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... (6 entities in total)
• 機能のキーワード: glycoside hydrolase, inverting, retaining, hydrolase
• 由来する生物種: Akkermansia muciniphila
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 205981.98

構造登録者

Chaberski, E.K.,Fredslund, F.,Teze, D.,Shuoker, B.,Kunstmann, S.,Karlsson, E.N.,Hachem, M.A.,Welner, D.H. (登録日: 2019-10-08, 公開日: 2020-02-26, 最終更新日: 2024-01-24)

• 主引用文献: Teze, D.,Shuoker, B.,Chaberski, E.K.,Kunstmann, S.,Fredslund, F.,Nielsen, T.S.,Stender, E.G.P.,Peters, G.H.J.,Nordberg Karlsson, E.,Welner, D.H.,Abou Hachem, M.; The Catalytic Acid-Base in GH109 Resides in a Conserved GGHGG Loop and Allows for Comparable alpha-Retaining and beta-Inverting Activity in an N-Acetylgalactosaminidase from Akkermansia muciniphila; Acs Catalysis, 2020; DOI: 10.1021/acscatal.9b04474

実験手法

X-RAY DIFFRACTION (2.13 Å)