6SZH

Acinetobacter baumannii undecaprenyl pyrophosphate synthase (AB-UppS) in complex with GW197

Summary for 6SZH

• Entry DOI: 10.2210/pdb6szh/pdb
• Descriptor: Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific), CALCIUM ION, 3,5-dimethyl-1~{H}-pyrrole-2-carbonitrile, ... (4 entities in total)
• Functional Keywords: inhibitor complex, transferase
• Biological source: Acinetobacter baumannii
• Total number of polymer chains: 2
• Total formula weight: 61969.98

Authors

Thorpe, J.H. (deposition date: 2019-10-02, release date: 2020-01-22, Last modification date: 2024-01-24)

• Primary citation: Thorpe, J.H.,Wall, I.D.,Sinnamon, R.H.,Taylor, A.N.,Stavenger, R.A.; Cocktailed fragment screening by X-ray crystallography of the antibacterial target undecaprenyl pyrophosphate synthase from Acinetobacter baumannii.; Acta Crystallogr.,Sect.F, 76:40-46, 2020; PubMed: 31929185; DOI: 10.1107/S2053230X19017199

Experimental method

X-RAY DIFFRACTION (1.65 Å)