6SXV

GH51 a-l-arabinofuranosidase soaked with aziridine inhibitor

Summary for 6SXV

Entry DOI	10.2210/pdb6sxv/pdb
Descriptor	GH51 a-l-arabinofuranosidase, [(1~{S},2~{S},3~{S},4~{S})-2-(hydroxymethyl)-3,4-bis(oxidanyl)cyclopentyl]azanium, GLYCEROL, ... (7 entities in total)
Functional Keywords	covalent complex, arabinofuranosidase, gh51, geobacillus, hydrolase
Biological source	Geobacillus stearothermophilus
Total number of polymer chains	2
Total formula weight	116265.68
Authors	McGregor, N.G.S.,Davies, G.J. (deposition date: 2019-09-26, release date: 2020-02-26, Last modification date: 2024-01-24)
Primary citation	McGregor, N.G.S.,Artola, M.,Nin-Hill, A.,Linzel, D.,Haon, M.,Reijngoud, J.,Ram, A.,Rosso, M.N.,van der Marel, G.A.,Codee, J.D.C.,van Wezel, G.P.,Berrin, J.G.,Rovira, C.,Overkleeft, H.S.,Davies, G.J. Rational Design of Mechanism-Based Inhibitors and Activity-Based Probes for the Identification of Retaining alpha-l-Arabinofuranosidases. J.Am.Chem.Soc., 142:4648-4662, 2020 Cited by PubMed: 32053363 DOI: 10.1021/jacs.9b11351 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.402 Å)

Structure validation