6SW6

Crystal structure R264H mutant of the human S-adenosylmethionine synthetase 1

Summary for 6SW6

Entry DOI	10.2210/pdb6sw6/pdb
Descriptor	S-adenosylmethionine synthase isoform type-1 (2 entities in total)
Functional Keywords	s-adenosylmethionine synthesis, transferase
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	87369.60
Authors	Panmanee, J.,Antonyuk, S.V.,Hasnain, S.S. (deposition date: 2019-09-19, release date: 2020-06-17, Last modification date: 2024-01-24)
Primary citation	Panmanee, J.,Antonyuk, S.V.,Hasnain, S.S. Structural basis of the dominant inheritance of hypermethioninemia associated with the Arg264His mutation in the MAT1A gene. Acta Crystallogr D Struct Biol, 76:594-607, 2020 Cited by PubMed: 32496220 DOI: 10.1107/S2059798320006002 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.85 Å)

Structure validation