6SUT

Crystal structure of phosphothreonine MCR-2

Summary for 6SUT

• Entry DOI: 10.2210/pdb6sut/pdb
• Descriptor: Putative integral membrane protein, ZINC ION, GLYCEROL, ... (5 entities in total)
• Functional Keywords: colistin, mcr, phosphoethanolamine, transferase, antimicrobial protein
• Biological source: Escherichia coli
• Total number of polymer chains: 1
• Total formula weight: 36674.90

Authors

Hinchliffe, P.,Spencer, J. (deposition date: 2019-09-16, release date: 2020-06-03, Last modification date: 2024-01-24)

• Primary citation: Lythell, E.,Suardiaz, R.,Hinchliffe, P.,Hanpaibool, C.,Visitsatthawong, S.,Oliveira, A.S.F.,Lang, E.J.M.,Surawatanawong, P.,Lee, V.S.,Rungrotmongkol, T.,Fey, N.,Spencer, J.,Mulholland, A.J.; Resistance to the "last resort" antibiotic colistin: a single-zinc mechanism for phosphointermediate formation in MCR enzymes.; Chem.Commun.(Camb.), 56:6874-6877, 2020; PubMed: 32432618; DOI: 10.1039/d0cc02520h

Experimental method

X-RAY DIFFRACTION (1.2 Å)