6SQ8

Structure of amide bond synthetase McbA from Marinactinospora thermotolerans

Summary for 6SQ8

Entry DOI	10.2210/pdb6sq8/pdb
Descriptor	Fatty acid CoA ligase, 1-ethanoyl-9~{H}-pyrido[3,4-b]indole-3-carboxylic acid, ADENOSINE MONOPHOSPHATE, ... (4 entities in total)
Functional Keywords	mcba, amide, atp, ligase, anl enzyme
Biological source	Marinactinospora thermotolerans
Total number of polymer chains	5
Total formula weight	268748.64
Authors	Rowlinson, B.,Petchey, M.,Grogan, G. (deposition date: 2019-09-03, release date: 2020-04-22, Last modification date: 2024-01-24)
Primary citation	Petchey, M.R.,Rowlinson, B.,Lloyd, R.C.,Fairlamb, I.J.S.,Grogan, G. Biocatalytic Synthesis of Moclobemide Using the Amide Bond Synthetase McbA Coupled with an ATP Recycling System. Acs Catalysis, 10:4659-4663, 2020 Cited by PubMed: 32337091 DOI: 10.1021/acscatal.0c00929 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.59 Å)

Structure validation