6SNY

Synthetic mimic of an EPCR-binding PfEMP1 bound to EPCR

Summary for 6SNY

• Entry DOI: 10.2210/pdb6sny/pdb
• Descriptor: Synthetic EPCR binding protein, Endothelial protein C receptor, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• Functional Keywords: pfemp1 epcr vaccine immunogen, immune system
• Biological source: synthetic construct; More
• Total number of polymer chains: 3
• Total formula weight: 64103.24

Authors

Barber, N.M.,Higgins, M.K. (deposition date: 2019-08-27, release date: 2019-09-04, Last modification date: 2021-01-20)

• Primary citation: Barber, N.M.,Lau, C.K.Y.,Turner, L.,Watson, G.,Thrane, S.,Lusingu, J.P.A.,Lavstsen, T.,Higgins, M.K.; Structure-Guided Design of a Synthetic Mimic of an Endothelial Protein C Receptor-Binding PfEMP1 Protein.; Msphere, 6:-, 2021; PubMed: 33408232; DOI: 10.1128/mSphere.01081-20

Experimental method

X-RAY DIFFRACTION (3.11 Å)